• Thanks for the important work you are doing. 

    ALL of you are great.

    -Jolene, Study Participant
  • It is a pleasure working with such a dedicated research team 

    and I would definitely like to collaborate with your site on future trials. I sincerely appreciate all of the efforts made to date on our studies!

    -GSK Monitor
  • Very pleasant and friendly staff.

    They are very considerate to make every effort to make me comfortable.

    -Ralph, Study Participant
  • I am never anxious on visits; 

    very helpful staff.

    -Donald, Study Participant
  • The staff is extremely welcoming and supportive

    Everyone is aware of their responsibilities, knowledgeable of research and very cooperative. The entire organization is well run from the top down. This is my favorite site to work with!

    -Novum Monitor
  • Everyone is friendly and very informative.

    They explain all procedures and why. The staff is courteous and friendly and they listen. They ask often if you need anything, are friendly and smiling. A smile always goes a long way, even when you don’t feel like smiling.

    -Diane, Study Participant
  • Awesome!

    -GSK Monitor
  • Well executed, punctual. 

    Good job, keep up the good work.

    -Joel, Study Participant
  • Laura R, Dr. Holcomb and the rest of the staff are super professionals! 

    Happy to be part of this study; will recommend this clinic to others!

    -Lou, Study Participant
  • Study Coordinators were very responsive to my emails 

    and requests for study questions. Staff at the site is very friendly and accommodating. Patients' charts are very well organized and complete

    -Quintiles Monitor
  • Wonderful!

    Everyone is so friendly each time I have an appointment.

    -Gloria, Study Participant
  • Lisa Lopez and the entire staff are extremely professional, courteous, welcoming, etc. 

    I never felt I was in a doctor’s office; it felt like being at home.

    -Sara, Study Participant
  • The staff was friendly and knowledgeable. 

    Principal Investigator was available to meet and showed oversight in source. Data and regulatory binders were clean and well maintained.

    -Wyeth Monitor
  • The staff is upbeat, friendly and positive. 

    Very willing to make the testing sessions as comfortable as if one is at home. The staff treats me with care, compassion and understanding.

    -Mary Ann, Study Participant
  • This site does quality work 

    and pays attention to detail. Data corrections are usually handled quickly. All staff seem organized and are conscientious about their work.

    -Sanofi Monitor
  • Educational, pleasant, concerned with my health, 

    as well as the study performance. A combination of professional and a concerned family.

    -Michael, Study Participant


Currently Enrolling

Research study of an Investigational vaccine for the potential prevention of primary C.difficile infection                                               

We are seeking subjects who:

Are male/female 50 years of age and older and

  • Have been hospitalized more than 2 days in the past year, or
  • Have been seen in an emergency room twice in the past year or resident in a nursing home? or
  • Have been to the doctor 10 or more times in the past year? or
  • Taken oral or injected antibiotics in the last 12 weeks?

Study participants will receive at no cost:

  • Study related medical exams
  • Compensation for travel and expenses
  • 3 doses of investigational vaccine or placebo and
  • Be followed up to 3 years after vaccination for potential Clostridium difficile infection


Call Diagnostics Research Group TODAY for more information at 210.692.7157!


What is Clostridium difficile (C-diff)?

Clostridium difficile is a bacterium that lives naturally within our intestines in a small percentage of humans but not all.  Other areas where the bacteria can thrive are soil, water, and both human and animal feces. Those who are carriers of the bacteria may never become ill or infected.

What are the symptoms of C-diff Infection?

Those who become ill may have a range of symptoms from diarrhea to life-threatening inflammation of the bowels.

What if I’m not a carrier, can I still get it?

Yes, you can. The bacteria produce spores that can live outside the body for many days.  Objects such as door knobs, bathroom fixtures, and other inanimate objects, particularly in hospitals, can become contaminated. If you touch a contaminated object, this does not mean you will automatically become ill.

Who is at risk for C-diff Infection?

Age:  Increasing age increases risk.

Current, recent or future hospitalizations:  the longer the stay, the greater the risk.

Recent use of antibiotics:  Antibiotics can alter the “good” flora within our intestines. This alteration can allow “bad” bacteria growth.

Immunocompromised:  Medical conditions that weaken the immune system.

Long term health care setting:  Nursing homes

How do I prevent C-diff Infection?

Contact Precautions such as hand washing are the best precaution but are not always effective. Alcohol sanitizers are ineffective against these bacteria.

Always wash your hands thoroughly before and after using the restroom.

Is there a vaccine to decrease my risk of C-diff Infection?

There are no currently approved vaccines, but there are research studies currently in progress.