P: 210-692-7157

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  • Staff is awesome!

    I would recommend you to join a study.

    -Cynthia, Study Participant

  • The friendliness of the staff, they validate parking if you park in the parking garage, very professional!

    I do recommend this research group!

    -Rosie, Study Participant

  • Your staff, including the parking attendant, are extremely welcoming and make me forget I'm here for a Doctor's visit.

    -Yvonne, Study Participant

  • Staff was very courteous

    -Leticia, Study Participant

  • Outstanding service and very friendly staff

    -Joseph, Study Participant

  • Every employee here has been polite, friendly and very kind.

    Really Enjoyed meeting everyone here.

    -Alex, Study Participant

  • Thanks for the important work you are doing. 

    ALL of you are great.

    -Jolene, Study Participant

  • It is a pleasure working with such a dedicated research team 

    and I would definitely like to collaborate with your site on future trials. I sincerely appreciate all of the efforts made to date on our studies!

    -GSK Monitor

  • Very pleasant and friendly staff.

    They are very considerate to make every effort to make me comfortable.

    -Ralph, Study Participant

  • I am never anxious on visits; 

    very helpful staff.

    -Donald, Study Participant

  • The staff is extremely welcoming and supportive

    Everyone is aware of their responsibilities, knowledgeable of research and very cooperative. The entire organization is well run from the top down. This is my favorite site to work with!

    -Novum Monitor

  • Everyone is friendly and very informative.

    They explain all procedures and why. The staff is courteous and friendly and they listen. They ask often if you need anything, are friendly and smiling. A smile always goes a long way, even when you don’t feel like smiling.

    -Diane, Study Participant

  • Awesome!

    -GSK Monitor

  • Well executed, punctual. 

    Good job, keep up the good work.

    -Joel, Study Participant

  • Laura R, Dr. Holcomb and the rest of the staff are super professionals! 

    Happy to be part of this study; will recommend this clinic to others!

    -Lou, Study Participant

  • Study Coordinators were very responsive to my emails 

    and requests for study questions. Staff at the site is very friendly and accommodating. Patients' charts are very well organized and complete

    -Quintiles Monitor

  • Wonderful!

    Everyone is so friendly each time I have an appointment.

    -Gloria, Study Participant

  • Lisa Lopez and the entire staff are extremely professional, courteous, welcoming, etc. 

    I never felt I was in a doctor’s office; it felt like being at home.

    -Sara, Study Participant

  • The staff was friendly and knowledgeable. 

    Principal Investigator was available to meet and showed oversight in source. Data and regulatory binders were clean and well maintained.

    -Wyeth Monitor

  • The staff is upbeat, friendly and positive. 

    Very willing to make the testing sessions as comfortable as if one is at home. The staff treats me with care, compassion and understanding.

    -Mary Ann, Study Participant

  • This site does quality work 

    and pays attention to detail. Data corrections are usually handled quickly. All staff seem organized and are conscientious about their work.

    -Sanofi Monitor

  • Educational, pleasant, concerned with my health, 

    as well as the study performance. A combination of professional and a concerned family.

    -Michael, Study Participant

Osteoarthritis of the Knee

Currently Enrolling

About Osteoarthritis

Osteoarthritis (OA) is the most common form of arthritis and is characterized by the loss of cartilage in a joint. As a result, the joint is painful and may have stiffness and swelling.

Osteoarthritis was previously known as degenerative arthritis because it was thought to be a natural result of the cumulative wear and tear associated with aging. While it is true that osteoarthritis generally has its onset after age 40, we know now that there are a number of factors which contribute to its development. For example, genetics, gender, obesity, and previous joint trauma, all appear to have a role.

OA affects 25 million adults in the U.S. The joint most likely to cause symptoms is the knee. This is one of the reasons that when studies of OA are performed, the knee model is most often used. As we age, osteoarthritis becomes more likely. Women are two to three times more likely to have OA symptoms than men. 

Other risk factors include injury, occurrence in other family members and certain occupations that require repetitive movement. A modifiable cause of OA is excess weight.