• Thanks for the important work you are doing. 

    ALL of you are great.

    -Jolene, Study Participant
  • It is a pleasure working with such a dedicated research team 

    and I would definitely like to collaborate with your site on future trials. I sincerely appreciate all of the efforts made to date on our studies!

    -GSK Monitor
  • Very pleasant and friendly staff.

    They are very considerate to make every effort to make me comfortable.

    -Ralph, Study Participant
  • I am never anxious on visits; 

    very helpful staff.

    -Donald, Study Participant
  • The staff is extremely welcoming and supportive

    Everyone is aware of their responsibilities, knowledgeable of research and very cooperative. The entire organization is well run from the top down. This is my favorite site to work with!

    -Novum Monitor
  • Everyone is friendly and very informative.

    They explain all procedures and why. The staff is courteous and friendly and they listen. They ask often if you need anything, are friendly and smiling. A smile always goes a long way, even when you don’t feel like smiling.

    -Diane, Study Participant
  • Awesome!

    -GSK Monitor
  • Well executed, punctual. 

    Good job, keep up the good work.

    -Joel, Study Participant
  • Laura R, Dr. Holcomb and the rest of the staff are super professionals! 

    Happy to be part of this study; will recommend this clinic to others!

    -Lou, Study Participant
  • Study Coordinators were very responsive to my emails 

    and requests for study questions. Staff at the site is very friendly and accommodating. Patients' charts are very well organized and complete

    -Quintiles Monitor
  • Wonderful!

    Everyone is so friendly each time I have an appointment.

    -Gloria, Study Participant
  • Lisa Lopez and the entire staff are extremely professional, courteous, welcoming, etc. 

    I never felt I was in a doctor’s office; it felt like being at home.

    -Sara, Study Participant
  • The staff was friendly and knowledgeable. 

    Principal Investigator was available to meet and showed oversight in source. Data and regulatory binders were clean and well maintained.

    -Wyeth Monitor
  • The staff is upbeat, friendly and positive. 

    Very willing to make the testing sessions as comfortable as if one is at home. The staff treats me with care, compassion and understanding.

    -Mary Ann, Study Participant
  • This site does quality work 

    and pays attention to detail. Data corrections are usually handled quickly. All staff seem organized and are conscientious about their work.

    -Sanofi Monitor
  • Educational, pleasant, concerned with my health, 

    as well as the study performance. A combination of professional and a concerned family.

    -Michael, Study Participant

Biogenics Research Chamber

About Biogenics Research Chamber











The Biogenics Research Chamber is a clinical research facility designed to conduct allergy exposure studies in a controlled environment.

Subjects are monitored continuously by highly trained investigators and staff.  Subject compliance and symptoms assessment are accurate and reproducible.

Our experienced team of principal investigators and clinicians are actively involved in the protocol design and conduct of all chamber studies.

Biogenics Research Chamber is ideal for proof of concept, dose ranging, mechanisms of action, and efficacy studies evaluating allergic rhinoconjunctivitis and asthma.

Our large database of potential study subjects and close cooperation with local academic investigators with expertise in molecular biology and genetics, allows us to perform studies at the leading edge of scientific discovery and design.


Allergens Validated in Biogenics Research Chamber


The Hill Country of Texas offers a unique opportunity for chamber testing utilizing this robust antigen. In the city of San Antonio, Mountain Cedar counts can exceed 50,000 grains/m3. It is estimated that 10-15% of the population living in Central Texas suffer from “Cedar Fever.” Our database contains over 4,500 participants with nasal and ocular symptoms due to Mountain Cedar pollen. Many pharmaceutical trials have successfully utilized the Mountain Cedar natural pollination season. Because of this unique situation, the first pollen validated in the Biogenics Research Chamber was Mountain Cedar. Our published data confirms the appropriateness of the chamber model utilizing this antigen.


Chamber studies have traditionally utilized ragweed pollen as the antigen. The Biogenics Research Chamber has performed validation studies utilizing ragweed pollen that, like Mountain Cedar pollen, elicited high nasal and ocular scores. Our database has more than 3,500 participants with symptoms from this ubiquitous allergen.


The Virginia Live Oak trees pollinate with vigor over a long spring season in Central Texas. With pollen counts that can rival Mountain Cedar in quantity, it is a very significant allergen in San Antonio. Validation studies in the chamber with this important spring allergen shows high nasal and ocular scores.



Perennial Allergic Rhinitis (PAR) is a year-round problem that causes significant allergy symptoms. The dominant cause of PAR on a world-wide basis is exposure to House Dust Mites. The Biogenics Research Chamber has performed successful validation studies utilizing the House Dust Mite antigen to show significant nasal and ocular symptoms.


Grass pollen sensitivity is a major cause of allergic rhinoconjunctivitis throughout the world, affecting the majority of atopic individuals. Biogenics Research Chamber is now validated to the Timothy Grass pollen.


Validation of other pollens and aeroallergens are ongoing.

Click here to learn more about Biogenics Research Chamber.